Cycloheximide, 5 g
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Molar mass (M) 281,36 g/mol
Melting point (mp) 112 °C
Storage temp. +4 °C
ADR 6.1 II
WGK 3
CAS No. [66-81-9]
EG-Nr. 200-636-0
UN-Nr. 2811
Stock solution: 10 mg/ml in H2O or acetone. Storage of stock solution at -20 °C. Working concentration: 1-10 µg/ml. Note: Inactivated at basic pH values. Heat- and acid stabile. No inactivation after 15 mins. 95 °C in pH 7.0.
€149.00/Pack Qty.
excl. VAT. | 5 g per Pack Qty.
Art. No. 8682.3
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Product details
Cycloheximide ≥98 %, for biochemistry
Antibiotic isolated from Streptomyces griseus. Its main biological activity is translation inhibition in eukaryotes by binding to the 60S subunit of the ribosomes. Cycloheximide inhibits binding of Aminoacyl-tRNA to the ribosomes, Peptidyltransferase, detachment of deacylated tRNA, and translocation of Aminoacyl-tRNA, resulting in cell growth arrest and apoptotic cell death. Not effective against bacteria. Cycloheximide is widely used for selection of cycloheximide-resistant strains of yeast and fungi, for inhibition of eukaryotic contaminants in bacterial microbiology, for controlled inhibition of protein synthesis in cell culture and for detection of short-lived proteins, and for apoptosis induction or facilitation of apoptosis induction by death receptors.
- Subtotal: 0.00
| Order No. | Pack Qty. | Pack. | Price | Quantity | ||
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| 8682.1 | 1 g | glass | €37.90 |
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| 8682.3 | 5 g | glass | €149.00 |
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| 8682.4 | 10 g | glass | €255.00 |
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Certificates of Analysis
Type analysis
| Appearance | white to off-white powder |
| Assay (HPLC) | ≥98 % |
| Water (KF) | ≤0,5 % |
| Specific rotation [α]a (c=1 % in CHCl3) | -32° to -26° |
| Ash content | ≤0,5 % |