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5-Ethynyl-2'-deoxyuridine (EdU), 5 mg

≥98 %
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
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Examples of effect: Have an allergenic effect, carcinogenic, mutagenic, toxic to reproduction and cause developmental toxicity (reprotoxic) or damage to organs Safety: You must be well-informed before starting work with these substances; wear protective clothing and gloves, eye protection and mask or breathing protection.
danger
H340-H361
i may cause genetic defects, suspected of damaging fertility or the unborn child
P280.0 P308+P313
i wear protective gloves/protective clothing/eye protection/face protection, IF exposed or concerned: Get medical advice/attention
Pack Qty.
Pack.
EdU
Empirical formula C11H12N2O5
Molar mass (M) 252,23 g/mol
Density (D) 1,6 g/cm³
Melting point (mp) 199 °C
Storage temp. -20 °C
Transport temp. cooled
WGK 3
CAS No. [61135-33-9]


Type analysis

CHF37.10/Pack Qty. 

excl. VAT. | 5 mg per Pack Qty.

Art. No. 7845.1

Available at short notice
Free of shipping costs from 200 CHF
from 6 Pack Qty. CHF35.24/Pack Qty.
from 24 Pack Qty. CHF33.39/Pack Qty.
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Technical Information
pKa (at 25 °C) ≥98 %  
5-Ethynyl-2'-deoxyuridine (EdU)
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Order No. Pack Qty. Pack. Price Quantity
7845.1 5 mg plastic CHF37.10
7845.2 10 mg plastic CHF56.70
7845.3 50 mg plastic CHF130.90
7845.4 100 mg plastic CHF208.60
7845.5 500 mg plastic CHF726.60
7845.6 1 g plastic CHF1,328.60
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General information

Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless‘ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1–3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.

References:1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.

Nucleosides and Nucleotides

Nucleosides

The detection of cell proliferation is of utmost importance for monitoring cell vitality, determining genotoxicity or evaluating anticancer drugs. The feeding of cells with EdU (5-ethynyl-2'-deoxyuridine) or EU (5-ethynyl uridine) can be used in cell proliferation studies.

Analysis certificates

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The following analysis certificates have been found:

Type analysis

Appearancewhite to off-white solid
Assay (HPLC)≥98 %

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