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Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA), 5 mg, 5 mg

From  baseclick
≥95 %, baseclick Grade
Icon_Baseclick_Logo-CMYK
Icon_Eisstern All products identified as being particularly temperaturesensitive are shipped in special ice boxes with freezer packs or in dry ice.
Examples of effect: Lead to damage to heath, cause irritation to eyes, skin or respiratory organs. Are fatal in larger quantities. Safety: As previously stated, in the event of skin irritation or contact with eyes, rinse with water or a suitable medium.
Warning
H315-H319-H335
i causes skin irritation, causes serious eye irritation, may cause respiratory irritation
P280 P302+P352 P305+P351+P338 P332+P313 P337+P313
i wear protective gloves/protective clothing/eye protection/face protection, IF ON SKIN: Wash with plenty of water, IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing, if skin irritation occurs: Get medical advice/attention, if eye irritation persists: Get medical advice/attention
Pack Qty.
Pack.
Packaging
THPTA
Empirical formula C18H30N10O3
Molar mass (M) 434,50 g/mol
Melting point (mp) 336 °C
Storage temp. -20 °C
Transport temp. cooled
WGK 1
CAS No. 760952-88-3

"baseclick-grade" water-soluble ligand in high quality for optimal yield
The water-soluble ligand THPTA is a very efficient additive for click reactions using CuSO4 as catalyst. It speeds-up the reactions plus maintaining the Cu(I) oxidation state of copper source to protect your biomolecules from damage and degradation.

€26.80/Pack Qty. 

excl. VAT. | 5 mg per Pack Qty.

Art. No. 7822.1

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Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA)
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Art. No. Pack Qty. Pack. Packaging Price Quantity
7822.1 5 mg plastic 5 mg

€26.80

7822.2 10 mg plastic 10 mg

€42.90

7822.3 50 mg plastic 50 mg

€88.05

7822.4 100 mg plastic 100 mg

€131.70

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Downloads / MSDS

General information

Tip:

Consumer Notice:

aqueous media: copper(II) sulfate 7816, sodium ascorbate 7819, THPTA 7822organic solvents (e.g. DMSO): Copper(I) bromide 7813, TBTA 7814 (copper stabilizing ligand)


Reagents for Click Chemistry

Starting from diverse copper catalyst sources, over Cu(I) stabilising ligands to buffer additives and solvents, you will find all necessary reagents in the special ROTI®Click quality to perform your click reactions here.


Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Click Chemistry

In recent years, click chemistry has become increasingly important and steadily more popular in research and development. The reasons for this are not only the easy handling and the high yields but also the countless application possibilities. Carl ROTH offers you the possibility to purchase the broad portfolio of click reagents, various kits for EdU-based cell proliferation assays and numerous other applications from the well-known brand baseclick. This enables us to offer you a necessary and comprehensive assortment for click chemistry.


Certificates of Analysis

You can search for and download your certificate of analysis for the selected product here. Please provide your batch number.
The following analysis certificates have been found:

Type analysis

Appearancewhite powder
Assay (HPLC)≥95 %