Technical Data Sheet
Geldanamycin, 1 mg
Molar mass (M) 560,64 g/mol
Melting point (mp) 275 °C
Storage temp. -20 °C
Transport temp. ambient temp.
WGK 1
CAS No. 30562-34-6
Photo sensitive! Store protected from light.
HSP90 inhibitor, tyrosine kinase inhibitor. Benzoquinone ansamycin antibiotic.
€88.70/Pack Qty.
excl. VAT. | 1 mg per Pack Qty.
Art. No. HN71.1
Product details
Geldanamycin ≥98 %, for biochemistry
Geldanamycin arrests cells in G2 phase, thus interfering with angiogenesis and oncogenesis. The specific binding of geldanamycin to heat shock protein 90 (HSP90) and its ER homologue GP96 leads to inhibition of the chaperone, results in degradation of HSP90 substrates and, subsequently, to deregulation of central cell mechanisms - cell cycle, cell proliferation, apoptosis/cell vitality.
Due to its antitumor potential it may be used as antibiotic against several eucaryotic carcinogenic cell lines. Additionally, geldanamycin is used as inhibitor of tyrosin-kinase and during analysis of several other physiological regulatory mechanisms.
Working concentration: 1-10 µg/ml.
Photo sensitive! Store protected from light.
- Subtotal: 0.00
| Art. No. | Pack Qty. | Pack. | Price | Quantity | |
|---|---|---|---|---|---|
| HN71.1 | 1 mg | glass |
€88.70 |
|
|
| HN71.2 | 5 mg | glass |
€213.95 |
|
|
| HN71.3 | 10 mg | glass |
€317.15 |
|
|
|
In stock
Available (note delivery time)
In procurement
No longer available
Delivery date currently unknown
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- Subtotal: 0.00
Downloads / MSDS
Certificates of Analysis
Type analysis
| Assay (HPLC) | ≥98 % |
| λ max. | 259 nm, 307 nm |
| Melting point | 258-262 °C |