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Cycloheximide, 1 g

≥98 %, for biochemistry
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Examples of effect: In smaller quantities, lead to immediate serious damage to health or death. Safety: Do not inhale, touch or swallow. Wear work safety equipment. Call a poison control centre or doctor immediately. Recovery position.
Examples of effect: Have an allergenic effect, carcinogenic, mutagenic, toxic to reproduction and cause developmental toxicity (reprotoxic) or damage to organs Safety: You must be well-informed before starting work with these substances; wear protective clothing and gloves, eye protection and mask or breathing protection.
Examples of effect: Are harmful to aquatic organisms, toxic or highly toxic, acute or with long-term effects. Safety: To be disposed of as hazardous waste only, do not allow into the environment under any circumstances.
Danger
H300-H341-H360D-H411
i fatal if swallowed, suspected of causing genetic defects, may damage the unborn child, toxic to aquatic life with long lasting effects
P202 P280 P301+P310 P308+P313 P391
i do not handle until all safety precautions have been read and understood, wear protective clothing/eye protection, IF SWALLOWED: Immediately call a POISON CENTER/doctor, IF exposed or concerned: Get medical advice/attention, collect spillage
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Actidione, Naramycin A
Empirical formula C15H23NO4
Molar mass (M) 281,36 g/mol
Melting point (mp) 112 °C
Storage temp. +4 °C
ADR 6.1 II
WGK 3
CAS No. [66-81-9]
EG-Nr. 200-636-0
UN-Nr. 2811

Glutarimid antibiotiotic, fungicidal
Stock solution: 10 mg/ml in H2O or acetone. Storage of stock solution at -20 °C. Working concentration: 1-10 µg/ml. Note: Inactivated at basic pH values. Heat- and acid stabile. No inactivation after 15 mins. 95 °C in pH 7.0.

Antibiotic isolated from Streptomyces griseus. Its main biological activity is translation in ...
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Type analysis

€40.75/Pack Qty. 

excl. VAT. | 1 g per Pack Qty.

Art. No. 8682.1

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from 6 Pack Qty. €38.71/Pack Qty.
from 24 Pack Qty. €36.68/Pack Qty.
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Cycloheximide ≥98 %, for biochemistry

Antibiotic isolated from Streptomyces griseus. Its main biological activity is translation inhibition in eukaryotes by binding to the 60S subunit of the ribosomes. Cycloheximide inhibits binding of Aminoacyl-tRNA to the ribosomes, Peptidyltransferase, detachment of deacylated tRNA, and translocation of Aminoacyl-tRNA, resulting in cell growth arrest and apoptotic cell death. Not effective against bacteria. Cycloheximide is widely used for selection of cycloheximide-resistant strains of yeast and fungi, for inhibition of eukaryotic contaminants in bacterial microbiology, for controlled inhibition of protein synthesis in cell culture and for detection of short-lived proteins, and for apoptosis induction or facilitation of apoptosis induction by death receptors.



Cycloheximide
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8682.1 1 g glass €40.75
8682.3 5 g glass €160.20
8682.4 10 g glass €274.15
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The following analysis certificates have been found:

Type analysis

Appearancewhite to off-white powder  
Assay (HPLC)≥98 %  
Water (KF)≤0,5 %  
Specific rotation [α]a (c=1 % in CHCl3)-32° to -26°  
Ash content≤0,5 %  

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