Novobiocin sodium salt, 10 g
Molar mass (M) 634,62 g/mol
Melting point (mp) 220 °C
Storage temp. +4 °C
CAS No. [1476-53-5]
Application: Stock solution: 100 mg/ml in H2O. Storage of stock solution: -20 °C. Working concentration: variable
excl. VAT. | 10 g per Pack Qty.
Art. No. 0247.3
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Novobiocin sodium salt ≥850 μg/mg, for biochemistry
Reduces growth of gram-positive bacteria by inhibition of initiation of DNA-synthesis via binding to ATP-binding sites of gyrase and topoisomerase. Novobiocin also interacts with the C-terminal ATP-binding site of HSP90, hence inhibiting its Chaperon quality. Also well suited as additive to microbiological nutrient media. Adding 40 mg/l Novobiocin during selective detection of coliform bacteria on Brilliant Green Bile broth (Art. No. CL06.1) efficiently reduces the growth of attendant flora (Alcaide et al., 1982, J. Appl. Bact. 53:143-6).
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|Specific rotation [α]a (dry substance)||-58° to -50°|
|pH value (2,5 % in H2O)||6,5-8,5|
|Sulphated ash||≤12,0 %|