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Radicicol, 1 mg

≥98 %, for biochemistry
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Examples of effect: In smaller quantities, lead to immediate serious damage to health or death. Safety: Do not inhale, touch or swallow. Wear work safety equipment. Call a poison control centre or doctor immediately. Recovery position.
Danger
H301-H315-H319-H335
i toxic if swallowed, causes skin irritation, causes serious eye irritation, may cause respiratory irritation
P270 P280 P301+P310 P302+P352 P305+P351+P338
i do not eat, drink or smoke when using this product, wear protective gloves/eye protection, IF SWALLOWED: Immediately call a POISON CENTER/doctor, IF ON SKIN: Wash with plenty of water, IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
Pack Qty.
Pack.
Empirical formula C18H17ClO6
Molar mass (M) 364,79 g/mol
Melting point (mp) 209 °C
Storage temp. -20 °C
Transport temp. ambient temp.
ADR 6.1 III
WGK 1
CAS No. 12772-57-5
UN-Nr. 2811

Strong HSP90 inhibitor, macrolactone antibiotic. Binds specifically to the heat shock protein HSP90.
Stock solution: 10 mg/ml (27 mM) in ethanol or DMSOStorage of stock solution at -20 °C, max. 2 weeks at 4 °CPhoto sensitive! Store protected from light.

The strong specific binding of radicicol to heat shock protein 90 (HSP90) leads to deregulation of its target mechanisms: cell cycle, cell proliferation, apoptosis/cell vitality. Also binds to yeast HSP90, E.coli HtpG and TRAP-1. Antifungal effects are probably caused by inactivation of chitin synthase in fungal cells.
Product details

€160.20/Pack Qty. 

excl. VAT. | 1 mg per Pack Qty.

Art. No. HN72.1

In stock
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from 6 Pack Qty. €152.19/Pack Qty.
from 24 Pack Qty. €144.18/Pack Qty.

Product details



Radicicol ≥98 %, for biochemistry

The strong specific binding of radicicol to heat shock protein 90 (HSP90) leads to deregulation of its target mechanisms: cell cycle, cell proliferation, apoptosis/cell vitality. Also binds to yeast HSP90, E.coli HtpG and TRAP-1. Antifungal effects are probably caused by inactivation of chitin synthase in fungal cells.


Directions for use

Working concentration: 5-300 µM



Radicicol
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Art. No. Pack Qty. Pack. Price Quantity
HN72.1 1 mg glass

€160.20

HN72.2 5 mg glass

€719.20

HN72.3 10 mg glass

€1,353.45

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Downloads / MSDS


Certificates of Analysis

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The following analysis certificates have been found:

Type analysis

Assay (HPLC)≥98 %