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Fmoc-L-Azidolysine, 1 g

PEPTIPURE® ≥98 %, for biochemistry
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Fmoc-L-Lys(N3)-OH, N-α-(9-Fluorenylmethoxycarbonyl)-ε-azido-L-lysine
Empirical formula C21H22N4O4
Molar mass (M) 394,42 g/mol
Melting point (mp) 78 °C
Storage temp. +4 °C
WGK 1
CAS No. 159610-89-6


€396.70/Pack Qty. 

excl. VAT. | 1 g per Pack Qty.

Art. No. 7357.2

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from 6 Pack Qty. €376.86/Pack Qty.
from 24 Pack Qty. €357.03/Pack Qty.

Product details



Fmoc-L-Azidolysine PEPTIPURE® ≥98 %, for biochemistry

Technical Information
Alternative Name Fmoc-L-Lys(N3)-OH 
Fmoc-L-Azidolysine
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7357.1 250 mg glass

€120.95

7357.2 1 g glass

€396.70

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Downloads / MSDS


General information

Amino acids

Our amino acids are of the highest purity and suitable for a broad range of applications in biochemistry. Besides the natural occurring L-amino acids, we offer a selection of unnatural D-amino acids and DL-amino acids.


Protected Amino Acids

We supply protected amino acids of the highest quality and purity for standard applications in biochemistry and specifically for peptide synthesis.


PEPTIPURE®-Reagents

Our Brand for Peptide Synthesis

Peptide synthesis reagents must meet very high requirements to ensure that no by-products are produced during peptide synthesis and that very high yields can be achieved. Under the brand name PEPTIPURE® you will find all reagents that are especially suitable for peptide synthesis.


Azido Amino Acids

With the emergence of click chemistry the use of azide- and alkyne-derivatised α-amino acids has found high interest e.g. in the area of peptide synthesis as a powerful tool in the development of new therapeutics and biological chemistry fundamental research. Peptide labelling mostly requires reactions which are running close to physiological conditions (neutral pH, aqueous solution, ambient temperature). Cu(I)-catalysed alkyne-azide cycloaddition (CuAAC) is optimal for such biological compounds, here the advantages of click chemistry once again show their potential. The low reactant concentrations, low background labelling, the quantitative and rapid labelling, plus the mild reaction conditions fit the necessary reactivity, selectivity and biocompatibility criteria for the peptide labelling and thus ensure the preservation of biological function. Carl ROTH provides high quality azido amino acids. In this form they can easily undergo click reaction when an alkyne functional reporter molecule is present.


Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Click Chemistry

In recent years, click chemistry has become increasingly important and steadily more popular in research and development. The reasons for this are not only the easy handling and the high yields but also the countless application possibilities. Carl ROTH offers you the possibility to purchase the broad portfolio of click reagents, various kits for EdU-based cell proliferation assays and numerous other applications from the well-known brand baseclick. This enables us to offer you a necessary and comprehensive assortment for click chemistry.


Certificates of Analysis

You can search for and download your certificate of analysis for the selected product here. Please provide your batch number.
The following analysis certificates have been found:

Type analysis

Appearancewhite crystalline powder
Assay (HPLC)≥98 %
Specific rotation [α]20D (c=1 in DMF)-14.0° to -12.0°