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E-64, 25 mg

≥99 %, for biochemistry
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N-(trans-epoxysuccinyl)-L-leucine-4-guanidinobutylamide, N-[N-(L-3-trans-Carboxyoxirane-2-carbonyl)leucyl]-agmatine
Empirical formula C15H27N5O5 · 0,5 H2O
Molar mass (M) 357,41 g/mol
Storage temp. -20 °C
Transport temp. ambient temp.
WGK 1
CAS No. 66701-25-5

Inhibitor of cysteine proteases.
Stock solution: 1 mM (360 µg/ml) in H2O, DMSO or ethanol. Storage of stock solution: at -20 °C max. 3 months.

Irreversible, strong and highly selective inhibition of cysteine protease (e. g. papain, bromelain, ficin, cathepsin B, H and L, tumor-cathepsin, calpain etc.). Does not inhibit serine proteases except trypsin.
Product details

€418.20/Pack Qty. 

excl. VAT. | 25 mg per Pack Qty.

Art. No. 2935.2

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Product details



E-64 ≥99 %, for biochemistry

Irreversible, strong and highly selective inhibition of cysteine protease (e. g. papain, bromelain, ficin, cathepsin B, H and L, tumor-cathepsin, calpain etc.). Does not inhibit serine proteases except trypsin.


Low toxicity, high cell permeability and stability against reducing reagents makes E-64 an excellent alternative to leupeptin or antipain.


Directions for use

Working concentration: 1-10 µM.



E-64
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2935.1 5 mg plastic

€110.20

2935.2 25 mg plastic

€418.20

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Downloads / MSDS


Certificates of Analysis

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The following analysis certificates have been found:

Type analysis

Appearancewhite powder
Assay (HPLC)≥99 %
Specific rotation [α]20D (in 0,1 N HCl)+21° to +26°