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E-64, 25 mg

≥99 %, for biochemistry
Pack Qty.
N-(trans-epoxysuccinyl)-L-leucine-4-guanidinobutylamide, N-[N-(L-3-trans-Carboxyoxirane-2-carbonyl)leucyl]-agmatine
Empirical formula C15H27N5O5 · 0,5 H2O
Molar mass (M) 357,41 g/mol
Melting point (mp) 182 °C
Storage temp. -20 °C
Transport temp. ambient temp.
CAS No. [66701-25-5]

Inhibitor of cysteine proteases.
Stock solution: 1 mM (360 µg/ml) in H2O, DMSO or ethanol.
Working concentration: 1–10 µM.
Storage of stock solution: at –20 °C max. 3 months.

Irreversible, strong and highly selective inhibition of cysteine protease (e.g. papain, bromelain, f ...
Product details
Type analysis

€325.20/Pack Qty. 

excl. VAT. | 25 mg per Pack Qty.

Art. No. 2935.2

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Product details

E-64 ≥99 %, for biochemistry

Irreversible, strong and highly selective inhibition of cysteine protease (e.g. papain, bromelain, ficin, cathepsin B, H and L, tumor-cathepsin, calpain etc.). Does not inhibit serine proteases except trypsin.

Low toxicity, high cell permeability and stability against reducing reagents makes E-64 an excellent alternative to leupeptin or antipain.

Technical Information
pKa (at 25 °C) ≥99 %  
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Order No. Pack Qty. Pack. Price Quantity
2935.1 5 mg plastic €91.30
2935.2 25 mg plastic €325.20
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Analysis certificates

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The following analysis certificates have been found:

Type analysis

Appearancewhite powder
Assay (HPLC)≥99 %
Spec. rotation [α]a (in 0,1 N HCl)+21° to +26°

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