5-Ethynyl-2'-deoxyuridine (EdU), 50 mg
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Molar mass (M) 252,23 g/mol
Density (D) 1,6 g/cm³
Melting point (mp) 199 °C
Storage temp. -20 °C
Transport temp. cooled
WGK 3
CAS No. [61135-33-9]
€108.50/Pack Qty.
excl. VAT. | 50 mg per Pack Qty.
Art. No. 7845.3
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- Subtotal: 0.00
| Order No. | Pack Qty. | Pack. | Price | Quantity | ||
|---|---|---|---|---|---|---|
| 7845.1 | 5 mg | plastic | €30.65 |
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| 7845.3 | 50 mg | plastic | €108.50 |
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| 7845.4 | 100 mg | plastic | €173.65 |
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| 7845.5 | 500 mg | plastic | €600.95 |
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General information
The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.
References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.
Nucleosides
The detection of cell proliferation is of utmost importance for monitoring cell vitality, determining genotoxicity or evaluating anticancer drugs. The feeding of cells with EdU (5-Ethynyl-2'-deoxyuridine) or EU (5-Ethynyl uridine) can be used in cell proliferation studies.
Certificates of Analysis
Type analysis
| Appearance | white to off-white solid |
| Assay (HPLC) | ≥98 % |