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5-Ethynyl uridine (EU), 10 mg

From  baseclick
≥98 %
Icon_Baseclick_Logo-CMYK
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Pack Qty.
Pack.
5-Ethynyl-U
Empirical formula C11H12N2O6
Molar mass (M) 268,22 g/mol
Storage temp. -20 °C
Transport temp. cooled
WGK 1
CAS No. 69075-42-9


€85.90/Pack Qty. 

excl. VAT. | 10 mg per Pack Qty.

Art. No. 7848.2

In production
from 6 Pack Qty. €81.60/Pack Qty.
from 24 Pack Qty. €77.31/Pack Qty.
5-Ethynyl uridine (EU)
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Art. No. Pack Qty. Pack. Price Quantity
7848.1 5 mg plastic

€53.65

7848.2 10 mg plastic

€85.90

7848.3 100 mg plastic

€518.15

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Downloads / MSDS

General information

Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Nucleosides and Nucleotides

Nucleosides

The detection of cell proliferation is of utmost importance for monitoring cell vitality, determining genotoxicity or evaluating anticancer drugs. The feeding of cells with EdU (5-Ethynyl-2'-deoxyuridine) or EU (5-Ethynyl uridine) can be used in cell proliferation studies.


Certificates of Analysis

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The following analysis certificates have been found:

Type analysis

Appearancewhite to light brown to light green powder
Assay (HPLC)≥98 %