Technical Data Sheet
Heparin sodium salt, 1 g, glass
Storage temp. +4 °C
WGK 1
CAS No. 9041-08-1
€138.70/Pack Qty.
excl. VAT. | 1 g per Pack Qty.
Art. No. 7692.1
Product details
Heparin sodium salt is a highly sulfated, water-soluble polysaccharide with strong anticoagulant properties. It acts as an indirect anticoagulant by enhancing the activity of antithrombin III, thereby inhibiting key coagulation factors such as thrombin and factor Xa. As a result, blood coagulation is effectively prevented or significantly slowed down.
Heparin sodium salt CELLPURE® ≥180 I.U./mg, Ph. Eur., from pork intestine mucosa
The product complies with Ph. Eur. quality and therefore meets the requirements of the European Pharmacopoeia with regard to defined standards for identity, purity, and potency.
The very low endotoxin content is in accordance with the specified limits for this quality. As a result, the product can generally also be used in sensitive applications such as cell culture. For cell culture applications, it is recommended to sterile-filter the solution prior to use.
| Endotoxin content | ≤ 0,01 EU/IU Heparin |
| Checked according to pharmacopoeia | Ph. Eur. |
- Subtotal: 0.00
| Art. No. | Pack Qty. | Pack. | Price | Quantity | |
|---|---|---|---|---|---|
| 7692.1 | 1 g | glass |
€138.70 |
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| 7692.2 | 5 g | glass |
€590.20 |
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| 7692.3 | 25 g | plastic |
€2,526.25 |
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In stock
Available (note delivery time)
In procurement
No longer available
Delivery date currently unknown
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- Subtotal: 0.00
Downloads / MSDS
General information
Carbohydrates or Saccharides make up 50 % of the dry biomass of the earth and are therefore the most frequent class of biomolecules. Besides at least two hydroxy groups, they also have an aldehyde or a ketone group and can be subdivided according to the number of monomeric components in mono-, di-, oligo and polysaccharides.
Whereas mono-, di- and oligosaccharides are soluble in water, taste sweet and are therefore called as sugar, polysaccharides are hardly, or not at all, soluble in water and have a neutral taste.
Carbohydrates, together with fats and proteins make up a large percentage of nutrition. In addition to their central role as an energy source, they are also an important structural component especially in plants (e.g. Cellulose). Ribose, a monosaccaride with five carbons (C5H10O5) is an essential element of coenzymes (such as ATP, FAD and NAD) and a structural component of RNA. Desoxyribose (a ribose derivative) is a structural component of DNA.
Oligo- and polysaccharides
Oligosaccharides consist of three to nine monosaccharide units.
Polysaccharides are macromolecular substances that consist of ≥10 monosaccharide units. A distinction is made between homoglycans, which are made up of only one type of monosaccharides (e.g. starch) and heteroglycans, which consist of at least two different monomeric components (e.g. xanthan).
In addition to the various nutrients in the medium, the pH value also plays a very important role in cell culture. The physiological pH for almost all mammalian cells is 7.4. Deviating from this, it has been observed that certain transformed cell lines prefer a pH between 7.0 and 7.4 and certain fibroblasts prefer a pH between 7.4 and 7.7. In any case, pH fluctuations should be avoided and the pH should be maintained as well as possible. That is why a buffer system in media is necessary. The most important buffer system in the body is the carbonic acid-carbonate buffer system. Accordingly, almost all cell culture media contain bicarbonate (NaHCO3). Bicarbonate alone leads to a strong pH increase of the medium, so that NaHCO3-buffered media must always be used with CO2 incubators. Depending on the NaHCO3 concentration in the medium, different CO2 environments are necessary to ensure a pH of about 7.4. For this reason, you should not work outside of the CO2 incubator for too long. If this is necessary, a HEPES buffer should be used in addition to the NaHCO3, which contributes as a second buffer system to stabilize the pH value.
Certificates of Analysis
Guarantee analysis
| Appearance | white to almost white, hygroscopic powder |
| Assay (dry substance) | ≥180 I.U./mg |
| Identity | complies |
| Appearance of solution | clear |
| pH value (1 %, H2O) | 5.5-8.0 |
| Loss on drying | ≤8.0 % |
| Endotoxins | ≤0.01 EU/IU Heparin |
| Protein (in dry substance) | ≤0.5 % |
| Nitrogen (dry substance) | 1.5-2.5 % |
| Sodium (dry substance) | 10.5-13.5 % |
| Nucleotidic impurities (260 nm) | ≤0.15 |
| Related Substances | |
| Sum of dermatan sulphate and chondroitin sulphate | ≤2.0 % |
| Any other impurities | complies |
| Bioburden (TAMC) | ≤10 cfu/g |
| Yeasts/Moulds (TYMC) | ≤10 cfu/g |