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H2N-PEG8-Azide, 10 mg

≥90 %
Icon_Eisstern All products identified as being particularly temperaturesensitive are shipped in special ice boxes with freezer packs or in dry ice.
Pack Qty.
Pack.
H2N-PEG8-Azide, 26-Azido-3,6,9,12,15,18,21,24-octaoxahexacosan-1-amine
Empirical formula C18H38N4O8
Molar mass (M) 438,52 g/mol
Density (D) 1 g/cm³
Storage temp. +4 °C
Transport temp. cooled
WGK 1
CAS No. [857891-82-8]

Linker

Type analysis

€75.80/Pack Qty. 

excl. VAT. | 10 mg per Pack Qty.

Art. No. 7829.2

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from 6 Pack Qty. €72.01/Pack Qty.
from 24 Pack Qty. €68.22/Pack Qty.
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H2N-PEG8-Azide
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7829.1 5 mg plastic €46.80
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General information

Azides & Alkynes

PEGylation and Linker

Click chemistry opens the door to introduce polyethylene glycols (PEGs) or other linkers in very sophisticated manner into your sample, which are still active for following reaction by the means of amine, carboxyl, malemide or NHS-functional terminal groups. You can choose between alkyne and azide structured PEGs and linkers which you find in the table below.


Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Certificates of Analysis

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The following analysis certificates have been found:

Type analysis

Appearanceyellowish liquid  
Assay≥90 %  

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