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NHS-PEG4-Azide, 5 mg

≥90 %
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Pack Qty.
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15-Azido-4,7,10,13-tetraoxapentadecanoic acid succinimidyl ester, NHS-PEG4-Azide
Empirical formula C15H24N4O8
Molar mass (M) 388,37 g/mol
Storage temp. -20 °C
Transport temp. cooled
WGK 1
CAS No. [944251-24-5]

Linker

Type analysis

€69.35/Pack Qty. 

excl. VAT. | 5 mg per Pack Qty.

Art. No. 7823.1

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NHS-PEG4-Azide
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7823.1 5 mg plastic €69.35
7823.2 10 mg plastic €100.55
7823.3 50 mg plastic €346.70
7823.4 100 mg plastic €659.55
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General information

Azides & Alkynes

PEGylation and Linker

Azides & AlkynesPEGylation and LinkerClick chemistry opens the door to introduce polyethylene glycols (PEGs) or other linkers in very sophisticated manner into your sample, which are still active for following reaction by the means of amine, carboxyl, malemide or NHS-functional terminal groups. You can choose between alkyne and azide structured PEGs and linkers which you find in the table below.


Click Chemistry

Click ChemistryThe copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Certificates of Analysis

You can search for and download your certificate of analysis for the selected product here. Please provide your batch number.
The following analysis certificates have been found:

Type analysis

Appearancecolourless viscous liquid  
Assay (NMR)≥90 %  
SolubilityDMSO, DMF, CH2Cl2  

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