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2-(Trimethylsilyl)ethoxymethyl chloride, 5 ml

≥95 %, for synthesis
Examples of effect: Flammable; liquids form compounds with the air which can become explosive; produce flammable gases with water or can self-combust. Safety: Keep away from open flames and sources of heat; close containers tightly; store in a fire-safe manner.
Examples of effect: Damage metals and burn body tissues; may cause serious eye damage. Safety: Avoid contact; wear safety spectacles and gloves. In the event of contact with eyes and skin, rinse with water.
Danger
H226-H314
i flammable liquid and vapour, causes severe skin burns and eye damage
P210 P280 P305+P351+P338 P310
i keep away from open flames and hot surfaces. No smoking, wear protective gloves/eye protection, IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing, immediately call a POISON CENTER/doctor
Pack Qty.
Pack.
Chloromethyl 2-trimethylsilylethyl ether, 2-(Chloromethoxy)ethyl trimethyl silane, SEM-chloride
Empirical formula SiC6H15OCl
Molar mass (M) 166,72 g/mol
Density (D) 0,94 g/cm³
Boiling point (bp) 172 °C
Flash point (flp) 46 °C
Storage temp. +4 °C
ADR 8 II
WGK 1
CAS No. 76513-69-4
EG-Nr. 278-483-4
UN-Nr. 2920

Protective group reagent

€131.70/Pack Qty. 

excl. VAT. | 5 ml per Pack Qty.

Art. No. 1444.2

In production
from 6 Pack Qty. €125.12/Pack Qty.
from 24 Pack Qty. €118.53/Pack Qty.

Product details



2-(Trimethylsilyl)ethoxymethyl chloride ≥95 %, for synthesis

Technical Information
Removal acidic 
alkaline 
fluoride ions 
Protecting group (short name) β-(Trimethylsilyl)ethoxymethyl (SEM) 
2-(Trimethylsilyl)ethoxymethyl chloride
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Art. No. Pack Qty. Pack. Price Quantity
1444.1 1 ml glass

€50.45

1444.2 5 ml glass

€131.70

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Downloads / MSDS


General information

Further attractive products to complete your chromatography laboratory can be found on our Chromatography page!


Protecting Groups

Today, protecting groups have become an important tool in the multistep, organic synthesis of complex compounds. The task of a protecting group is to protect a functional group from undesirable reactions with other functional groups. Then the protecting group should be cleaved under as mild conditions as possible. Good protecting groups should be specific, highly selective and both introduceable and cleavable in high yields, and stable under as many reaction conditions as possible.


Derivatisation Reagents for GC

Derivatisation reagents are used mainly in gas chromatography when adequate volatility or stability of the substances to be separated is required. Detection sensitivity can also be increased through derivatisation.

Our range of derivatisation reagents is ideal for acylation, alkylation and silylation of reagents.


Certificates of Analysis

You can search for and download your certificate of analysis for the selected product here. Please provide your batch number.
The following analysis certificates have been found:

Type analysis

Appearanceclear,colourless liquid
Assay (H-NMR)≥95 %