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DMT removal reagent, 2.5 l

for DNA synthesis
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Examples of effect: Damage metals and burn body tissues; may cause serious eye damage. Safety: Avoid contact; wear safety spectacles and gloves. In the event of contact with eyes and skin, rinse with water.
Examples of effect: Lead to damage to heath, cause irritation to eyes, skin or respiratory organs. Are fatal in larger quantities. Safety: As previously stated, in the event of skin irritation or contact with eyes, rinse with water or a suitable medium.
Examples of effect: Have an allergenic effect, carcinogenic, mutagenic, toxic to reproduction and cause developmental toxicity (reprotoxic) or damage to organs Safety: You must be well-informed before starting work with these substances; wear protective clothing and gloves, eye protection and mask or breathing protection.
Examples of effect: Are harmful to aquatic organisms, toxic or highly toxic, acute or with long-term effects. Safety: To be disposed of as hazardous waste only, do not allow into the environment under any circumstances.
Danger
H315-H318-H335-H336-H351-H411
i causes skin irritation, causes serious eye damage, may cause respiratory irritation, may cause drowsiness or dizziness, suspected of causing cancer, toxic to aquatic life with long lasting effects
P280 P302+P352 P305+P351+P338 P308+P313
i wear protective clothing/eye protection/face protection, IF ON SKIN: Wash with plenty of soap and water, IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing, IF exposed or concerned: Get medical advice/attention
Pack Qty.
Pack.
3 % Trichloro acetic acid in dichloromethane
Density (D) 1,32 g/cm³
Boiling point (bp) 40 °C
Melting point (mp) -95 °C
ADR 6.1 II
WGK 2
UN-Nr. 2927

for DNA synthesis with ABI™ Synthesizer
3 % TCA in DCM. Thread sizes: 450 ml - 27 mm. The 2.5 l bottle can be used with all instruments.

Dimethoxytrityl is a protective group for hydroxy groups which is used to protect the 5' OH group of the individual nucleotides in DNA synthesis. The protective group is acid labile and is removed in the ongoing synthesis reaction by the addition of trifluoroacetic acid (deprotection) to enable the coupling of the subsequent nucleotide.
Product details

€188.15/Pack Qty. 

excl. VAT. | 2.5 l per Pack Qty.

Art. No. 2257.2

In production
from 4 Pack Qty. €178.74/Pack Qty.
from 24 Pack Qty. €169.34/Pack Qty.

Product details



DMT removal reagent for DNA synthesis

Dimethoxytrityl is a protective group for hydroxy groups which is used to protect the 5' OH group of the individual nucleotides in DNA synthesis. The protective group is acid labile and is removed in the ongoing synthesis reaction by the addition of trifluoroacetic acid (deprotection) to enable the coupling of the subsequent nucleotide.


We offer DMT-Removal-Reagent in dichloroethane (K060) as well as in dichloromethane (2257). DMT in DCE is used for synthesizers which draw the solution from the bottles by vacuum pumps and push it through the reaction columns. Since these vacuum pumps apply a significant force, the DCE is more suitable due to its high boiling pressure, as it is absorbed and introduced into the reaction without the formation of gas bubbles. The use of DMT in DCM could interfere with the reaction by creating gas bubbles.



DMT removal reagent
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2257.2 2.5 l glass

€188.15

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Downloads / MSDS


Certificates of Analysis

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The following analysis certificates have been found:

Type analysis

Appearanceclear solution
Assay (TCA)2,90-3,10 %
Water (KF)≤0,005 %