Guanidine thiocyanate, 100 g
Molar mass (M) 118,16 g/mol
Density (D) 1,29 g/cm³
Melting point (mp) 121 °C
ADR 8 II
CAS No. [593-84-0]
For a 4 M solution, solubilise 472,64 g in distilled water and fill to 1 l.
Stock solution: 4 M or 8 M in water. Storage of stock solution: +4 °C. Working concentration: 4 M in hydrous buffer system (e.g. 25 mM sodium citrate, 0,5 % SDS)
excl. VAT. | 100 g per Pack Qty.
Art. No. 0017.1
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Guanidine thiocyanate ≥99 %, for biochemistry
Highly chaotropic agent that potently destroys the three-dimensional structure of proteins, leading to denaturation. Guanidinium (iso)thiocyanate contains potent anionic as well as cationic groups, that form strong hydrogen bonds. It, therefore, can be used to break protein disulfide bonds as well as to disrupt hydrophobic interactions, and is added during RNA extraction in order to inhibit RNAse activity.
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|Appearance (33 %, water)||colourless, clear|
|Melting point||118-121 °C|
|Iron (Fe)||≤0,0001 %|
|Heavy metals||≤0,001 %|
|pH value (1 M, H2O)||5,0-7,0|