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HPLC column NUCLEODUR® C18 Pyramid

From  Macherey-Nagel
Material: stainless steel.
Particle size
Column length
Column inner diameter

Product details

€747.15/Pack Qty. 

excl. VAT. | 1 unit(s) per Pack Qty.

Art. No. 1L7E.1

Ready for dispatch in 3-4 weeks
from 6 Pack Qty. €709.79/Pack Qty.
from 24 Pack Qty. €672.44/Pack Qty.

Product details

Material: stainless steel.

  • Octadecyl phase with polar endcapping
  • Carbon content: 14.0 %
  • Pore size: 110 Å
  • pH stability: 1-9
  • Eluent on column: acetonitrile/water

Basic pharmaceuticals, very polar compounds, organic acids, analgesics, complexing agents, nucleic acid bases, organic acids, penicillin antibiotics, water-soluble vitamins, USP L1, suitable for 100 % aqueous eluents, suitable for LC-MS.

Similar phases:
Aqua®, Synergi® Hydro-RP; AQ; Atlantis® dC18; Polaris® C18-A.

Further attractive products to complete your chromatography laboratory can be found on our Chromatography page!

For protection of your main HPLC column from contamination, it is recommended to use guard columns. These short columns are placed into a guard column holder. The guard column holder in combination with a guard column inside is installed between the injector and the HPLC column. This installation prevents chemical impurities to reach the main column. Because a contamination could form an irreversible bond with the column packing material (stationary phase) and this can result in shorter column life. If you want to prolong the lifetime of your main column, then these short columns can help you.

Further HPLC columns from Macherey-Nagel available on request.

The Egyptian pyramids were built near the Nile so that the stone blocks could be transported by water.

HPLC Columns NUCLEODUR® “Pyramid”

The polar endcapping makes this C18 phase suitable for aqueous eluents and is also referred to as an “aqua column”.

Recommended application(s):

  • In general, compounds with ionisable functional groups such as basic pharmaceuticals and pesticides e.g. analgesics, anti-inflammatories, antidepressants, herbicides, phytopharmaceuticals, immunosuppressants.
  • USP L1 (C18) · USP L7 (C8)

HPLC column NUCLEODUR® C18 Pyramid 

Technical Information
Particle size 5 µm
Column length 250 mm
Column inner diameter 4 mm
Column volume 3.15 ml
Endcapped yes 
Eluent in column Acetonitrile - Water 
Phase C18 Pyramid 
Surface chemistry Octadecyl (C18, ODS) modification, Polar endcapping 
USP listing L1 
Separation principle Reversed phase (RP) 
Column shape Analytical separation column 
Column type HPLC column 
Particle type Fully porous particles (FPP) 
Specific surface according to BET 340 m²/g
Pore volume 0.9 ml/g
Pore size 110 Å
Temperature stability 60 °C 
Pressure stability 600 bar 
pH stability 1,0-9,0 
Recommended application(s) Analgesics, Complexing agents, Nucleic acid bases, Organic acids, Penicillin antibiotics, Suitable for 100 % aqueous eluents, Water-soluble vitamins 
Similar phases Aqua® 
Synergi™ Hydro-RP 
Atlantis® dC18 
Polaris® C18-A 
HPLC column NUCLEODUR® C18 Pyramid
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Art. No. Particle size Column length Column inner diameter Pack Qty. Price Quantity
1L7E.1 5 µm 250 mm 4 mm 1 unit(s)


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General information

Further attractive products to complete your chromatography laboratory can be found on our Chromatography page!


NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. We offer two phases NUCLEODUR® Gravity which is ideal for sophisticated analytical separations and NUCLEODUR® ec suitable for routine HPLC analysis.