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Geneticin disulphate (G418 Sulphate), 10 g

≥650 U/mg, for biochemistry
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Examples of effect: Have an allergenic effect, carcinogenic, mutagenic, toxic to reproduction and cause developmental toxicity (reprotoxic) or damage to organs Safety: You must be well-informed before starting work with these substances; wear protective clothing and gloves, eye protection and mask or breathing protection.
Danger
H317-H334
i may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled
P260 P302+P352 P342+P311
i do not breathe dust, IF ON SKIN: Wash with plenty of water, if experiencing respiratory symptoms: Call a POISON CENTER/doctor
Pack Qty.
Pack.
Antibiotic G 418
Empirical formula C20H40N4O10 · 2 H2SO4
Molar mass (M) 692,70 g/mol
Melting point (mp) 139 °C
Storage temp. +4 °C
WGK 1
CAS No. [108321-42-2]

Aminoglycoside antibiotic
Application: Selection of transfected eukaryotic cells. Resistance gene: Neomycin. Stock solution: 10-50 mg/ml in H2O or culture medium. Storage of stock solution: -20 °C. Working concentration: 50-1000 µg/ml, has to be established for each cell type.

Inhibits protein biosynthesis by binding to ribosomes, particularly to eukaryotic 80S ribosomes. Through interference with the tRNA docking process, sequence errors appear and the elongating peptide chain is truncated. Geneticin disulphate unspecifically effects all cells, and is highly toxic for eukaryotic cells. Resistance is mediated by the bacterial enzyme aminoglycoside-3-phosphotransferase.
Product details
Type analysis

€589.00/Pack Qty. 

excl. VAT. | 10 g per Pack Qty.

Art. No. 0239.4

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from 6 Pack Qty. €559.55/Pack Qty.
from 24 Pack Qty. €530.10/Pack Qty.
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Personal technical advice on this product
Dr Belenki
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Product details



Geneticin disulphate (G418 Sulphate) ≥650 U/mg, for biochemistry

Inhibits protein biosynthesis by binding to ribosomes, particularly to eukaryotic 80S ribosomes. Through interference with the tRNA docking process, sequence errors appear and the elongating peptide chain is truncated. Geneticin disulphate unspecifically effects all cells, and is highly toxic for eukaryotic cells. Resistance is mediated by the bacterial enzyme aminoglycoside-3-phosphotransferase.



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0239.1 250 mg glass €34.50
0239.2 500 mg glass €46.50
0239.3 1 g glass €85.90
0239.4 10 g glass €589.00
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Type analysis

Activity≥650 U/mg  
Water (KF)≤10 %  

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