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4-Azidobenzoic acid

≥97 %
Icon_Eisstern All products identified as being particularly temperaturesensitive are shipped in special ice boxes with freezer packs or in dry ice.
Examples of effect: Flammable; liquids form compounds with the air which can become explosive; produce flammable gases with water or can self-combust. Safety: Keep away from open flames and sources of heat; close containers tightly; store in a fire-safe manner.
Warning
H228
i flammable solid
P210
i keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking
Pack Qty.
Pack.
Empirical formula C7H5N3O2
Molar mass (M) 163,14 g/mol
Melting point (mp) 176 °C
Storage temp. +4 °C
Transport temp. cooled
ADR 4.1 III
WGK 1
CAS No. [6427-66-3]
UN-Nr. 1325

Linker

Type analysis

€38.50/Pack Qty. 

excl. VAT. | 10 mg per Pack Qty.

Art. No. 7835.1

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General information

Azides & Alkynes

PEGylation and Linker
Click chemistry opens the door to introduce polyethylene glycols (PEGs) or other linkers in very sophisticated manner into your sample, which are still active for following reaction by the means of amine, carboxyl, malemide or NHS-functional terminal groups. You can choose between alkyne and azide structured PEGs and linkers which you find in the table below.


Click Chemistry

The copper(I)‑catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Analysis certificates

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The following analysis certificates have been found:

Type analysis

Appearancewhite, crystalline powder  
Assay (HPLC)≥97 %  

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