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Geneticin disulphate (G418) solution, 100 ml

CELLPURE® 50 mg/ml, sterile
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Icon_Steril Sterile products
Examples of effect: Have an allergenic effect, carcinogenic, mutagenic, toxic to reproduction and cause developmental toxicity (reprotoxic) or damage to organs Safety: You must be well-informed before starting work with these substances; wear protective clothing and gloves, eye protection and mask or breathing protection.
Danger
H317-H334
i may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled
P302+P352 P304+P341 P333+P313
i IF ON SKIN: Wash with plenty of water, IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing, if skin irritation or rash occurs: Get medical advice/attention
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Pack.
G418 sulphate solution, G418 solution
Empirical formula C20H40N4O10 · 2 H2SO4
Molar mass (M) 692,70 g/mol
Density (D) 1 g/cm³
Boiling point (bp) 100 °C
Storage temp. +4 °C
WGK 1
CAS No. [108321-42-2]

Aminoglycoside antibiotic. Stock solution, for cell culture, biochemistry and molecular biology. Inhibits protein biosynthesis by binding to ribosomes, particularly to eukaryotic 80S ribosomes.
Working concentration: 50-1000 µg/ml, has to be determined for each cell type.

Through interference with the tRNA docking process, sequence errors appear and the elongating peptide chain is truncated. Geneticin disulphate unspecifically effects all cells, and is highly toxic for eukaryotic cells. Resistance is mediated by the bacterial enzyme aminoglycoside-3-phosphotransferase.
Product details
Type analysis
€345.65 /Pack Qty.

€258.95/Pack Qty.  Campaign price!

excl. VAT. | 100 ml per Pack Qty.

Art. No. CP11.3

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Product details



Geneticin disulphate (G418) solution CELLPURE® 50 mg/ml, sterile

Through interference with the tRNA docking process, sequence errors appear and the elongating peptide chain is truncated. Geneticin disulphate unspecifically effects all cells, and is highly toxic for eukaryotic cells. Resistance is mediated by the bacterial enzyme aminoglycoside-3-phosphotransferase.


Application: Selection of transfected eukaryotic cells. Resistance gene: Neomycin.


Endotoxins: <10 E.U./ml.



Technical Information
Endotoxin content <10 E.U./ml 
Geneticin disulphate (G418) solution
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Order No. Pack Qty. Pack. Price Quantity
CP11.1 10 ml plastic €54.40
CP11.2 20 ml plastic €72.90
CP11.3 100 ml plastic €258.95
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The following analysis certificates have been found:

Type analysis

Concentration50 mg/ml  
Activity (powder)>600 µg/mg  
Endotoxins<10 EU/ml  
Sterilitycomplies  
Suitability for cell culturcomplies  
pH value5,0-6,0  

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