3-Azido-7-hydroxycoumarin, 1 mg
Molar mass (M) 203,15 g/mol
Storage temp. –20 °C
Transport temp. cooled
WGK 1
CAS No. [817638-68-9]
For a 10 mM solution: add 492 µl to 1 mg.
€94.50/Pack Qty.
excl. VAT. | 1 mg per Pack Qty.
Art. No. 7811.1

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Product details
3-Azido-7-hydroxycoumarin ≥98 %
Emissions maximum | 480 nm (nach Click-Reaktion) |
- Subtotal: 0.00
Order No. | Pack Qty. | Pack. | Price | Quantity | ||
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7811.1 | 1 mg | plastic | €94.50 |
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7811.2 | 5 mg | plastic | €316.60 |
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General information
The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.
References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.
Fluorescent Tags
Carl ROTH offers a selection of fluorescent tags for labelling of (bio-)molecules via click chemistry. All available tags are suitable for fluorescence spectroscopy applications due to their excellent absorption properties and good solubility. Tags with PEG-spacer are beneficial for applications with as little interaction between the analyte and the tag as possible. The coumarine derivative (Art No. 7811) offers a unique feature: fluorescence is only detected after the coupling via click reaction.
Certificates of Analysis
Type analysis
Appearance | brown solid |
Assay (HPLC) | ≥98 % |
Absorption max. (buffer, pH 7) | 404 nm (after click reaction) |
Emission max. (buffer, pH 7) | 480 nm (after click reaction) |
Solubility | DMSO, DMF, MeOH, MeCN |