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5-Ethynyl uridine (EU), 5 mg

≥98 %
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Empirical formula C11H12N2O6
Molar mass (M) 268,22 g/mol
Storage temp. -20 °C
Transport temp. cooled
WGK 1
CAS No. [69075-42-9]


Type analysis
€61.20 /Pack Qty.

€48.90/Pack Qty.  Campaign price!

excl. VAT. | 5 mg per Pack Qty.

Art. No. 7848.1

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Technical Information
pKa (at 25 °C) ≥98 %  
5-Ethynyl uridine (EU)
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Order No. Pack Qty. Pack. Price Quantity
7848.1 5 mg plastic €48.90
7848.2 10 mg plastic €82.95
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General information

Click Chemistry

The copper(I)‑catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1–3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.

References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.

Nucleosides and Nucleotides

Nucleosides

The detection of cell proliferation is of utmost importance for monitoring cell vitality, determining genotoxicity or evaluating anticancer drugs. The feeding of cells with EdU (5-Ethynyl-2'-deoxyuridine) or EU (5-Ethynyl uridine) can be used in cell proliferation studies.

Analysis certificates

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The following analysis certificates have been found:

Type analysis

Appearancewhite to almost white solid  
Assay (HPLC)≥98 %  

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