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5-Ethynyl-2'-deoxyuridine (EdU), 5 mg

Van  baseclick
≥98 %
Icon_Baseclick_Logo-CMYK
Icon_Eisstern All products identified as being particularly temperaturesensitive are shipped in special ice boxes with freezer packs or in dry ice.
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Mogelijke gevolgen: veroorzaken allergieën, kankerverwekkend (carcinogeen), verandering erfelijk materiaal (mutageen), brengt de voortplanting in gevaar en vruchtbeschadigend (reprotoxisch) of orgaanbeschadigend Veiligheid: voor het werk met dergelijke stoffen moet men zich goed informeren; veiligheidskleding en handschoenen, oog- en mondbescherming of adembescherming dragen.
Danger
H340-H361
i may cause genetic defects, suspected of damaging fertility or the unborn child
P201 P308+P313
i obtain special instructions before use, IF exposed or concerned: Get medical advice/attention
VE
Verp.
5-Ethynyl-dU, EdU
Empirical formula C11H12N2O5
Molar mass (M) 252,23 g/mol
Storage temp. -20 °C
Transport temp. cooled
WGK 3
CAS No. 61135-33-9

Clickable EdU allows detection of de novo DNA
5-Ethynyl-2’-deoxyuridine (5-EdU) is a nucleoside analog to thymidine and can be incorporated into DNA during DNA synthesis (see also our EdU cell proliferation assays for more information). The newly synthesized DNA carries an alkyne moiety that can be easily clicked to azides to assess cell proliferation, cell cycles, viability, etc.

26,80 €/VE 

Excl. btw | 5 mg Per VE

Bestelnr. 7845.1

Beschikbaar
Vrij van verzendingskosten vanaf 250 €
Klaar voor verzending in 1-2 weken
Vanaf 6 VE 25,46 €/VE
Vanaf 24 VE 24,12 €/VE
5-Ethynyl-2'-deoxyuridine (EdU)
Geselecteerde hoeveelheid:   0
  1. Tussentotaal:  0.00
Bestelnr. VE Verp. Prijs Hoeveelheid
7845.1 5 mg plastic

26,80 €

7845.3 50 mg plastic

81,60 €

7845.4 100 mg plastic

123,65 €

7845.5 500 mg plastic

430,00 €

7845.6 1 g plastic

661,15 €

Op voorraad
Beschikbaar
In bestelling
Niet meer verkrijgbaar
Leveringsdatum onbekend
Geselecteerde hoeveelheid:   0
  1. Tussentotaal:  0.00

Downloads / MSDS

Algemene informatie

Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Click Chemistry

In recent years, click chemistry has become increasingly important and steadily more popular in research and development. The reasons for this are not only the easy handling and the high yields but also the countless application possibilities. Carl ROTH offers you the possibility to purchase the broad portfolio of click reagents, various kits for EdU-based cell proliferation assays and numerous other applications from the well-known brand baseclick. This enables us to offer you a necessary and comprehensive assortment for click chemistry.


Nucleosides and Nucleotides

Nucleosides

The detection of cell proliferation is of utmost importance for monitoring cell vitality, determining genotoxicity or evaluating anticancer drugs. The feeding of cells with EdU (5-Ethynyl-2'-deoxyuridine) or EU (5-Ethynyl uridine) can be used in cell proliferation studies.


Analysecertificaten

Hier kunt u uw analysecertificaat voor het geselecteerde product zoeken en downloaden. Geef een chargenummer op.
De volgende analysecertificaten werden gevonden:

Type analysis

Appearancewhite to off-white solid
Assay (HPLC)≥98 %