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Cycloheximide, 5 g
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Molar mass (M) 281,36 g/mol
Melting point (mp) 112 °C
Storage temp. +4 °C
ADR 6.1 II
WGK 3
CAS No. 66-81-9
EG-Nr. 200-636-0
UN-Nr. 2811
Stock solution: 10 mg/ml in H2O or acetone.
Storage of stock solution at -20 °C.
Working concentration: 1-10 µg/ml.
Note: Inactivated at basic pH values. Heat- and acid stabile. No inactivation after 15 mins. 95 °C in pH 7.0.
198,90 €/VE
Excl. btw | 5 g Per VE
Bestelnr. 8682.3
Productdetails
Cycloheximide ≥90 %, for biochemistry
Antibiotic isolated from Streptomyces griseus. Its main biological activity is translation inhibition in eukaryotes by binding to the 60S subunit of the ribosomes. Cycloheximide inhibits binding of Aminoacyl-tRNA to the ribosomes, Peptidyltransferase, detachment of deacylated tRNA, and translocation of Aminoacyl-tRNA, resulting in cell growth arrest and apoptotic cell death.
Not effective against bacteria. Cycloheximide is widely used for selection of cycloheximide-resistant strains of yeast and fungi, for inhibition of eukaryotic contaminants in bacterial microbiology, for controlled inhibition of protein synthesis in cell culture and for detection of short-lived proteins, and for apoptosis induction or facilitation of apoptosis induction by death receptors.
- Tussentotaal: 0.00
| Bestelnr. | VE | Verp. | Prijs | Hoeveelheid | |
|---|---|---|---|---|---|
| 8682.1 | 1 g | glass |
49,35 € |
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| 8682.3 | 5 g | glass |
198,90 € |
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| 8682.4 | 10 g | glass |
349,40 € |
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- Tussentotaal: 0.00
Downloads / MSDS
Analysecertificaten
Type analysis
| Appearance | white to off-white powder |
| Assay (HPLC) | ≥90 % |
| Loss on drying | ≤1.0 % |
| Activity | ≥900 U/mg |