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Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA), 10 mg

≥95 %, ROTI®Click Grade
Icon_Eisstern All products identified as being particularly temperaturesensitive are shipped in special ice boxes with freezer packs or in dry ice.
Przykłady działania: prowadzą do uszczerbku na zdrowiu, drażnią oczy, skórę lub organy układu oddechowego. W dużych ilościach prowadzą do śmierci. Bezpieczeństwo: jak wyżej, w razie podrażnienia skóry lub kontaktu z oczami przepłukać wodą lub innym odpowiednim środkiem.
Warning
H315-H319-H335
i causes skin irritation, causes serious eye irritation, may cause respiratory irritation
P260 P302+P352 P305+P351+P338
i do not breathe dust, IF ON SKIN: Wash with plenty of water, IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing
Pack Qty.
Pack.
THPTA
Empirical formula C18H30N10O3
Molar mass (M) 434,50 g/mol
Storage temp. -20 °C
Transport temp. cooled
WGK 1
CAS No. [760952-88-3]

Ligand for Click Chemistry
For a 0,1 M solution: add 230 l to 10 mg.

Type analysis

50,50 €/op. 

plus VAT | 10 mg za op.

Nr kat. 7822.2

Dostępny z magazynu w Karlsruhe
Szybka, prosta i niezawodna dostawa.
od 6 op. 47,98 €/op.
od 24 op. 45,45 €/op.
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Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA)
Wybrana ilość:   0
  1. Suma pośrednia:  0.00
Nr kat. Pack Qty. Pack. Cena Ilość
7822.1 5 mg plastic 34,90 €
7822.2 10 mg plastic 50,50 €
7822.3 50 mg plastic 86,50 €
7822.4 100 mg plastic 144,50 €
Dostępny z magazynu w Karlsruhe
Dostępny krótkoterminowo
Niedostępny
Data dostawy obecnie nieznana
Wybrana ilość:   0
  1. Suma pośrednia:  0.00

Pobranie


Informacje ogólne

Click Chemistry

The copper(I)-catalysed azide-alkyne cycloaddition (CuAAC) is the most prominent example of a group of reactions named click reactions. According to Sharpless’ definition, these reactions are characterised by high yields, mild reaction conditions, and by their tolerance of a broad range of functional groups.[1-3] Typically, the reactions require simple or no workup or purification of the product. The most important characteristic of the CuAAC reaction is its unique bioorthogonality as neither azide nor terminal alkyne functional groups are generally present in natural systems.


References:
1 H. C. Kolb, M.G. Finn, K. B. Sharpless, Angew. Chem. Int. Ed. 2001, 40, 2004-2021.
2 C.W. Tornoe, C. Christensen, M. Meldal, J. Org. Chem. 2002, 67, 3057-3064.
3 V. V. Rostovtsev, L. G. Green, V. V. Fokin, K. B. Sharpless, Angew. Chem. 2002, 114, 2708-2711; Angew. Chem. Int. Ed. 2002, 41, 2596-2599.


Tip:

TBTA (Art.No. 7814) is suitable as copper-stabilising ligand for reactions in organic solvents. THPTA (Art.No. 7822) on the other hand is an optimal ligand for reactions in aqueous media.


Reagents for Click Chemistry

Starting from diverse copper catalyst sources, over Cu(I) stabilising ligands to buffer additives and solvents, you will find all necessary reagents in the special ROTI®Click quality to perform your click reactions here.


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Type analysis

Appearancewhite powder  
Assay (HPLC)≥95 %  
SolubilityH2O, DMSO/t-Butanol Solvent  

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