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Geldanamycin, 1 mg

≥98 %, for biochemistry
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Pack Qty.
Empirical formula C29H40N2O9
Molar mass (M) 560,64 g/mol
Melting point (mp) 275 °C
Storage temp. -20 °C
Transport temp. ambient temp.
CAS No. [30562-34-6]

HSP90 inhibitor, tyrosine kinase inhibitor. Benzoquinone ansamycin antibiotic. Binds specifically to the heat shock protein HSP90.
Application: Stock solution: 1000x in DMSO or methanol. Storage of stock solution at -20 °C, max. 2 weeks at 4 °C. Working concentration: 1-10 µg/ml. Photo sensitive! Store protected from light.

The specific binding of geldanamycin to heat shock protein 90 (HSP90) and its ER homologue GP96 lead ...
Szczegóły dotyczące produktu
Type analysis

67,50 €/op. 

plus VAT | 1 mg za op.

Nr kat. HN71.1

Dostępny krótkoterminowo
od 6 op. 64,12 €/op.
od 24 op. 60,75 €/op.
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Szczegóły dotyczące produktu

Geldanamycin ≥98 %, for biochemistry

The specific binding of geldanamycin to heat shock protein 90 (HSP90) and its ER homologue GP96 leads to inhibition of the chaperone, results in degradation of Hsp90 substrates and, subsequently, to deregulation of central cell mechanisms - cell cycle, cell proliferation, apoptosis/cell vitality. Geldanamycin arrests cells in G2 phase, thus interfering with angiogenesis and oncogenesis. Due to its antitumor potential it may be used as antibiotic against several eucaryotic carcinogenic cell lines. Additionally, geldanamycin is used as inhibitor of tyrosin-kinase and during analysis of several other physiological regulatory mechanisms.

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Nr kat. Pack Qty. Pack. Cena Ilość
HN71.1 1 mg glass 67,50 €
HN71.2 5 mg glass 165,90 €
HN71.3 10 mg glass 239,00 €
Dostępny z magazynu w Karlsruhe
Dostępny krótkoterminowo
Data dostawy obecnie nieznana
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Type analysis

Assay (HPLC)≥98 %  
λ max.259 nm, 307 nm  
Melting point258-262 °C  

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