Przejdź do treści Przejdź do menu nawigacyjnego

Geldanamycin, 1 mg

≥98 %, for biochemistry
Icon_EVE-EUD Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Pack Qty.
Pack.
Empirical formula C29H40N2O9
Molar mass (M) 560,64 g/mol
Melting point (mp) 275 °C
Storage temp. -20 °C
Transport temp. ambient temp.
WGK 1
CAS No. [30562-34-6]

HSP90 inhibitor, tyrosine kinase inhibitor. Benzoquinone ansamycin antibiotic. Binds specifically to the heat shock protein HSP90.
Application: Stock solution: 1000x in DMSO or methanol. Storage of stock solution at -20 °C, max. 2 weeks at 4 °C. Working concentration: 1-10 µg/ml. Photo sensitive! Store protected from light.

The specific binding of geldanamycin to heat shock protein 90 (HSP90) and its ER homologue GP96 lead ...
Szczegóły dotyczące produktu
Type analysis

67,50 €/op. 

plus VAT | 1 mg za op.

Nr kat. HN71.1

Dostępny krótkoterminowo
od 6 op. 64,12 €/op.
od 24 op. 60,75 €/op.
Usługa abonamentowa firmy Carl Roth

Now recurring orders conveniently delivered as a subscription!

With the new Carl Roth Replenishment Service you can let products be ordered automatically which you need regularly in your lab!

How it works:
1

Put all products for your subscription in the desired quantity in the basket.

2

In the shopping cart, select the option "Order shopping cart as subscription" Order as subscription.

3

Set Starty point and interval for your subscription and submit order!

By the way: Through your account you can customize or delete your subscriptions anytime.

Czy masz pytania do tego produktu?

Do you have a question about this product?

In the general information or Product details, we have compiled extensive descriptions and downloads for each product.
If you can not find an answer to your question in the Certificates of Analysis and Application Examples , feel free to contact us!
Contact Service

Szczegóły dotyczące produktu



Geldanamycin ≥98 %, for biochemistry

The specific binding of geldanamycin to heat shock protein 90 (HSP90) and its ER homologue GP96 leads to inhibition of the chaperone, results in degradation of Hsp90 substrates and, subsequently, to deregulation of central cell mechanisms - cell cycle, cell proliferation, apoptosis/cell vitality. Geldanamycin arrests cells in G2 phase, thus interfering with angiogenesis and oncogenesis. Due to its antitumor potential it may be used as antibiotic against several eucaryotic carcinogenic cell lines. Additionally, geldanamycin is used as inhibitor of tyrosin-kinase and during analysis of several other physiological regulatory mechanisms.



Geldanamycin
Wybrana ilość:   0
  1. Suma pośrednia:  0.00
Nr kat. Pack Qty. Pack. Cena Ilość
HN71.1 1 mg glass 67,50 €
HN71.2 5 mg glass 165,90 €
HN71.3 10 mg glass 239,00 €
Dostępny z magazynu w Karlsruhe
Dostępny krótkoterminowo
Niedostępny
Data dostawy obecnie nieznana
Wybrana ilość:   0
  1. Suma pośrednia:  0.00

Pobranie


Świadectwa jakości

Tu możesz wyszukać i pobrać świadectwo jakości wybranego produktu. Wpisz numer serii.
Znaleziono następujące świadectwa jakości:

Type analysis

Assay (HPLC)≥98 %  
λ max.259 nm, 307 nm  
Melting point258-262 °C  

0 Oceny

0.0 z 5 gwiazdek