Technical Data Sheet
Collagen type I, native, 10 g
Transport temp. ambient temp.
WGK 1
CAS No. 9007-34-5
EG-Nr. 232-697-4
Soluble, molecular collagen with intact native triple helix as well as N- and C-terminal telopeptides (telocollagen).
€449.00/Pack Qty.
excl. VAT. | 10 g per Pack Qty.
Art. No. 23M7.2
Product details
Collagen is the most abundant protein in mammals and currently comprise 28 tissue-specific collagen types (Collagen Type I to XXVIII). They perform important structural, biomechanical, and organizational functions in tissues such as skin, bone, cartilage, and tendons. Furthermore, they support cell interactions and regulate processes such as cell growth, migration, and differentiation.
Collagen type I, native CELLPURE® >50%, Ultra Quality, bovine, acid soluble
This is acid-soluble, native Collagen Type I (Acid Soluble Collagen, ASC) derived from bovine hides sourced from BSE-safe countries in accordance with ISO 22442. Due to the gentle manufacturing process, the collagen is present as native, molecular telocollagen with preserved triple helix structure and intact N- and C-terminal telopeptides. The natural, intact structure ensures full biological activity of the collagen, including integrin-mediated cell adhesion as well as the ability to self-assemble into fibrillar collagen suprastructures.
These biological properties make telocollagen an optimal biomaterial and an important foundation for tissue repair, regeneration, and biomedical research. Furthermore, it serves as a versatile building block for materials science.
Collagen Type I is provided as a flake-like substrate (>50% collagen, <50% water) and is characterized by good solubility in slightly acidic as well as aqueous solutions, enabling simple and reproducible handling. The controlled manufacturing process ensures particularly high purity, characterized by very low endotoxin and total microbial count (TMC) levels.
- Native triple-helix structure
- Intact telopeptides (telocollagen)
- Full biological activity
- High biocompatibility
- Endotoxin-free
- Very good solubility
- 3D cell culture
- Surface coating
- In vitro fibrillogenesis
- Tissue engineering
- Manufacture of bioinks
- Regenerative medicine
| Endotoxin content | ≤0,5 U/mg |
| Additional info | Source: Bovine |
- Subtotal: 0.00
| Art. No. | Pack Qty. | Pack. | Price | Quantity | |
|---|---|---|---|---|---|
| 23M7.1 | 2 g | plastic |
€116.00 |
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| 23M7.2 | 10 g | plastic |
€449.00 |
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In stock
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- Subtotal: 0.00
Downloads / MSDS
Certificates of Analysis
Guarantee analysis
| Appearance | flake-like white to off-white particles |
| Identity (SDS-PAGE) | typical collagen band pattern of α-chains and β- and γ-components |
| Purity (SDS-PAGE) | collagen only; no other proteins detectable |
| Onset | ≥40.0 °C |
| enthalpy | ≥50 J/g |
| Dry substance | ≥50 % |
| Solubility | soluble in 5 mM acetic acid solution |
| Volatile parts | ≤50 % |
| residual acetic acid content | ≤1.0 % |
| Sulphated ash | ≤2.0 % |
| Hydroxyproline content (dry substance) | 9.0-11.0 % |
| Na (Sodium) | ≤1.0 % |
| Heavy metals (total): lead, mercury, bismuth, arsenic, antimony, tin, cadmium, copper, molybdenum, silver | ≤10 ppm |
| Endotoxins (LAL) | ≤0.5 EU/mg |
| Bioburden (TMC) | ≤100 cfu/g |
| Fibrillar precipitation | corresponds to collagen fibril formation (Williams et al., Journal of Biological Chemistry, 1978) |