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Geneticin disulphate (G418) solution, 100 ml

50 mg/ml, BioScience Grade, sterile, ready-to-use
Icon_Steril Sterile products
Icon_ready-to-use Ready-to-use products and reagents
Examples of effect: Have an allergenic effect, carcinogenic, mutagenic, toxic to reproduction and cause developmental toxicity (reprotoxic) or damage to organs Safety: You must be well-informed before starting work with these substances; wear protective clothing and gloves, eye protection and mask or breathing protection.
Danger
H317-H334
i may cause an allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled
P280 P302+P352 P304+P341 P333+P313
i wear protective gloves/eye protection, IF ON SKIN: Wash with plenty of water, IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing, if skin irritation or rash occurs: Get medical advice/attention
Sterile
Pack Qty.
Pack.
G418 sulphate solution, G418 solution
Empirical formula C20H40N4O10 · 2 H2SO4
Molar mass (M) 692,70 g/mol
Density (D) 1 g/cm³
Boiling point (bp) 100 °C
Melting point (mp) 0 °C
Storage temp. +4 °C
WGK 1
CAS No. [108321-42-2]

Aminoglycoside antibiotic.
Working concentration: 50-1000 µg/ml, has to be determined for each cell type.

Inhibits protein biosynthesis by binding to ribosomes, particularly to eukaryotic 80S ribosomes.
Through interference with the tRNA docking process, sequence errors appear and the elongating peptide chain is truncated. Geneticin disulphate unspecifically effects all cells, and is highly toxic for eukaryotic cells. Resistance is mediated by the bacterial enzyme aminoglycoside-3-phosphotransferase.
Product details
€403.15 /Pack Qty.

€322.50/Pack Qty.  Campaign price!

excl. VAT. | 100 ml per Pack Qty.

Art. No. 2039.3

In production
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Product details

Sterile


Geneticin disulphate (G418) solution 50 mg/ml, BioScience Grade, sterile, ready-to-use

Inhibits protein biosynthesis by binding to ribosomes, particularly to eukaryotic 80S ribosomes.
Through interference with the tRNA docking process, sequence errors appear and the elongating peptide chain is truncated. Geneticin disulphate unspecifically effects all cells, and is highly toxic for eukaryotic cells. Resistance is mediated by the bacterial enzyme aminoglycoside-3-phosphotransferase.


Extracted from Micromonospora rhodorangea.


Application: Selection of transfected eukaryotic cells.
Resistance gene: Neomycin.



Technical Information
Use Sterile stock solution, suitable for cell culturing, as well as for biochemical and biomolecular assays. 
Geneticin disulphate (G418) solution
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Order No. Pack Qty. Pack. Price Quantity
2039.1 10 ml plastic
€73.00

€58.35

2039.2 20 ml plastic
€99.90

€79.85

2039.3 100 ml plastic
€403.15

€322.50

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The following analysis certificates have been found:

Type analysis

Concentration50 ± 10 mg/ml
Active assay≥700 µg/mg
Sterilitycomplies