Phenylmethyl sulphonyl fluoride, 25 g, plastic
Please consider that this product might be liable to some legal sanctions as for example to obtain an end user declaration or the prohibition of some applications. For details please do contact your counterpart in our sales department!
Molar mass (M) 174,2 g/mol
Density (D) 0,79 g/cm³
Melting point (mp) 94 °C
ADR 8 II
WGK 1
CAS No. [329-98-6]
EG-Nr. 206-350-2
UN-Nr. 2923
Stock solution: 17.4 mg/ml (100 mM) in isopropanol, ethanol or methanol.
Storage of stock solution protected from light at -20 °C.
For your convenience, Art. No. 6367.4 comes packed in a 30 ml brown glass bottle. Addition of 20 ml 2-propanol results in a 100 mM stock solution.
Reversible inhibitor of cysteine-proteases. Ki = 0.91 ±0.01 mM
€117.20/Pack Qty.
excl. VAT. | 25 g per Pack Qty.
Art. No. 6367.2
Now recurring orders conveniently delivered as a subscription!
With the new Carl Roth Replenishment Service you can let products be ordered automatically which you need regularly in your lab!
How it works:Put all products for your subscription in the desired quantity in the basket.
In the shopping cart, select the option "Order shopping cart as subscription" Order as subscription.
Set Starty point and interval for your subscription and submit order!
By the way: Through your account you can customize or delete your subscriptions anytime.
Product details
Phenylmethyl sulphonyl fluoride ≥98 %, for biochemistry
General, irreversible inhibitor of serin proteases (chymotrypsin, trypsin and thrombin) and for the dystin-protease papain. Inhibiton by sulphonation of the serine localised in the enzymatic active site.
Reversible inhibitor of cysteine-proteases. Ki = 0.91 ±0.01 mM
Working concentration: 17-174 µg/ml (0,1-1 mM).
Dissolves easily in isopropanol, ethanol and methanol. Not stable in aqueous solutions (half-life value of 1 h at pH 7.5/RT).
For stock solutions of 200-250 mM heat shortly (approx. 30 mins) to 30 °C.
Stock solutions should be stored at -20 °C. Short term storage of few weeks may be done at +4 °C in the dark.
PMSF reacts with thiols. DTT and β-mercaptoethanol reduce the inhibitory effect.
At every stage of isolating or purifying the proteins, PMSF should be added fresh from the stock solution. PMSF is often not sufficient as the only protease inhibitor in the preparation to protect against decomposition processes, as for example high salt concentration (3.0 M) impairs the inhibitory effect of PMSF.
- Subtotal: 0.00
| Order No. | Pack Qty. | Pack. | Price | Quantity | ||
|---|---|---|---|---|---|---|
| 6367.1 | 5 g | plastic |
€35.40 |
|
||
| 6367.2 | 25 g | plastic |
€117.20 |
|
||
| 6367.3 | 100 g | plastic |
€327.90 |
|
||
| 6367.4 | 348 mg | glass |
€17.10 |
|
||
|
In stock
In procurement
Not available
Delivery date currently unknown
|
||||||
- Subtotal: 0.00
Downloads / MSDS
Certificates of Analysis
Type analysis
| Appearance | White to beige powder or crystals |
| Assay | ≥98 % |
| Identity (Raman) | complies |
| Melting point | 91-95 °C |
| Solubility in ethanol | complies |
| Solubility in methanol | complies |