Oxidation reagent, 2.5 l
Boiling point (bp) 65 °C
Flash point (flp) -21 °C
Melting point (mp) -108,5 °C
ADR 3 II
excl. VAT. | 2.5 l per Pack Qty.
Art. No. 2254.3
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Oxidation reagent for DNA synthesis
0,05 M Iodine
The phosphite triester linkage formed during oligonucleotide synthesis is of limited stability and has to stabilised. Treatment of the support-bound material with iodine and water in the presence of a weak base oxidizes the phosphite triester into a tetracoordinated phosphate triester, a protected precursor of the naturally occurring phosphate diester internucleosidic linkage.
|Instructions for use, addition||Suitable for Expedite™89xx and Polygen®|
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