Technical Data Sheet
anti-Desmoplakin 1/2 mouse monoclonal, DP 1 + 2-2.15, 0.2 ml
Boiling point (bp) ~100 °C
Storage temp. +4 °C
Transport temp. ambient temp.
€123.65/Pack Qty.
excl. VAT. | 0.2 ml per Pack Qty.
Art. No. 1NP7.1
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Product details
This antibody portfolio includes a wide range of tissue- & tumor-specific primary antibodies for basic research, product development and analysis of a variety of biological questions. The monoclonal antibodies are perfectly applicable for all cell or tissue biology studies and for the analysis of predictive markers in research.
- High epitope affinity
- Highly specific detection of the target protein
- Unconjugated
- Suitable for e.g. western blot, immunoprecipitation, ELISA & immunofluorescence
anti-Desmoplakin 1/2 mouse monoclonal, DP 1 + 2-2.15 50 μg/ml, monoclonal, affinity purified
DP1 + 2-2.15 shows distinct punctate membrane staining of different epithelia.
Tumors specifically detected: primary and metastatic carcinoma and meningioma.
Polypeptides reacting: desmoplakin 1 and 2 (Mr 250,000 and 215,000). The epitope recognized by clone DP1 + 2-2.15 is mapped to the N-terminus of the rod domain (Bornslaeger, E. A., 1996).
Bornslaeger, E. A. Breaking the connection: displacement of the desmosomal plaque protein desmoplakin from cell-cell interfaces disrupts anchorage of intermediate filament bundles and alters intercellular junction assembly. J. Cell Biol. 134, 9851001 (1996).
Host: mouse
Antibody type: monoclonal
Isotype: IgG1
Clone: DP1 + 2-2.15
Immunogen: bovine desmoplakin 1 + 2
UniprotID: A0A3Q1MR22 (bovine), E1BWI0 (chicken), P15924 (human), E9Q557 (mouse), Q8VBY1 (rat)
Synonym: desmoplakin, DP, 250/210 kDa paraneoplastic pemphigus antigen, DSP
Conjugate: unconjugated
Purification: affinity chromatography
Intended use: research use only
Application: ICC/IF, IHC, WB
Reactivity: bovine, chicken, human, mouse, rat
Immunocytochemistry (ICC): Assay dependent
Immunohistochemistry (IHC) - frozen: 1:10-1:50 (1-5 μg/ml)
Immunohistochemistry (IHC) - paraffin: 1:10-1:50 (1-5 μg/ml, microwave treatment recommended)
Western Blot (WB): assay dependent
- Subtotal: 0.00
| Art. No. | Pack Qty. | Pack. | Price | Quantity | |
|---|---|---|---|---|---|
| 1NP7.1 | 0.2 ml | plastic |
€123.65 |
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| 1NP7.2 | 1 ml | plastic |
€310.70 |
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